You are currently viewing In vitro CRISPR-Cas Cleavage Assays Streamline Gene Editing Workflows
Scientist working with microscope in laboratory. Medical research

In vitro CRISPR-Cas Cleavage Assays Streamline Gene Editing Workflows

[et_pb_section fb_built=”1″ _builder_version=”4.21.2″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.21.2″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.21.2″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.26.1″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″]

Origionally posted on CRISPR QC’s website: https://crisprqc.com/wp-content/uploads/2024/08/20240806-CRISPR-Cleave-Case-Study-Layout.pdf

 

Key Takeaways:

  • CRISPR QC’s in vitro CRISPR-Cas cleavage assays can streamline CRISPR workflows by identifying optimal gRNAs and Cas proteins early in the process, saving time and resources typically spent on less effective candidates.
  • The CRISPR Analytics Platform revealed significant differences in Cas9 protein activity across different vendors.
  • In vitro cleavage data from the CRISPR Analytics Platform correlated positively with in vivo editing outcomes in transgenic mosquitoes, increasing customer confidence in proceeding with gene editing designs.

To read the full case study, go to CRISPR QC’s website: https://crisprqc.com/wp-content/uploads/2024/08/20240806-CRISPR-Cleave-Case-Study-Layout.pdf

[/et_pb_text][/et_pb_column][/et_pb_row][/et_pb_section]